{"id":21631,"date":"2017-01-13T12:41:00","date_gmt":"2017-01-13T12:41:00","guid":{"rendered":"http:\/\/143.198.236.18\/?p=21631"},"modified":"2023-09-08T09:28:50","modified_gmt":"2023-09-08T09:28:50","slug":"us-generics-price-increases","status":"publish","type":"post","link":"https:\/\/fideres.com\/us-generics-price-increases\/","title":{"rendered":"US Generics Price Increases"},"content":{"rendered":"<h2>Key Points<\/h2>\n<ul>\n<li>Generic drug price increases may be more widespread than the scope of any current lawsuit.<\/li>\n<li>Fideres has identified over 90 generic drugs with anomalous price increases.<\/li>\n<\/ul>\n<h2>Rising Number of Generic Drug Lawsuits<\/h2>\n<p style=\"font-weight: 400;\">Since Senator Sanders&#8217; initial 2014 investigation into drug prices, there have been over 68 antitrust lawsuits concerning over 10 different generic drugs. Fideres has found anomalous pricing patterns for a much larger number of drugs than what is covered by the current 68 cases, the DOJ investigation and the lawsuit filed by the Attorney Generals of 20 U.S. States, all alleging price-fixing.<\/p>\n<p style=\"font-weight: 400;\">Below is a timeline of cases filed concerning generic drug pricing:<img decoding=\"async\" loading=\"lazy\" class=\" wp-image-29074 aligncenter\" src=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1.png\" alt=\"\" width=\"984\" height=\"595\" srcset=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1.png 1637w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1-300x181.png 300w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1-1024x619.png 1024w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1-768x464.png 768w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture1-Number-of-Cases-filed-1-1536x928.png 1536w\" sizes=\"(max-width: 984px) 100vw, 984px\" \/><\/p>\n<h2>Number of Americans Affected<\/h2>\n<p style=\"font-weight: 400;\">There are a number of factors that make generic drugs highly susceptible to collusion:<\/p>\n<ul style=\"font-weight: 400;\">\n<li>3 in 5 American adults in 2015 were taking at least one prescription drug<sup>1\u00a0<\/sup><\/li>\n<li>As of 2014, over 88% of all prescriptions in the US were for generic drugs<sup>2<\/sup><\/li>\n<li>In 2014, this meant that nearly 3.8 billion prescriptions were for generics<sup>3<\/sup><\/li>\n<\/ul>\n<p>A report from the Government Accountability Office stated that more than 20% of the 1,441 generic drugs examined by the department had experienced a price hike of 100% or more between 2010 and 2015.<\/p>\n<h2>Regional Phenomenon<\/h2>\n<p>The phenomenon appears to be limited to the US generic drugs market. Fideres compared drug prices for a sample of drugs in the US, Norway, Denmark, and the UK and found that, over the period of 2010-2015, generic prices for the sample remained roughly constant outside the US. Other aspects of the US generics drug market include high barriers to entry and high market concentration among manufacturers.<\/p>\n<h2>Barriers to Entry<\/h2>\n<p>Obtaining the rights to manufacture generic drugs is a lengthy process, even for specialized companies within the field. Drug manufacturing faces intense regulatory oversight and high manufacturing costs for every drug made. To bring a new generic drug to the market, manufacturers require an Abbreviated New Drug Application (ANDA). This takes on average 36 months to be approved by the FDA. However, the process can be lengthened if the FDA requires any amendments to the ANDA (Tier 1 &amp; 2).<\/p>\n<p>A sample timeline is below:<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-29075 \" src=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-2-ANDA-Timeline-e1693904802834-1024x469.png\" alt=\"\" width=\"963\" height=\"441\" srcset=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-2-ANDA-Timeline-e1693904802834-1024x469.png 1024w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-2-ANDA-Timeline-e1693904802834-300x137.png 300w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-2-ANDA-Timeline-e1693904802834-768x352.png 768w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-2-ANDA-Timeline-e1693904802834.png 1444w\" sizes=\"(max-width: 963px) 100vw, 963px\" \/><\/p>\n<h6 style=\"text-align: center;\"><em><span style=\"font-size: 10pt;\">Source:\u00a0 FDA, statnews.com<\/span><\/em><\/h6>\n<h2 style=\"text-align: left;\">Market Concentration<\/h2>\n<p>High market concentration makes it easier for manufacturers to implement price-fixing schemes. In the generic drugs market, drug manufacturer concentration is commonly ranked by the DOJ as highly concentrated.<\/p>\n<p>The following chart shows the market concentration for a sample drug:<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-29077 size-large\" src=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-4-HHI-1024x661.png\" alt=\"\" width=\"1024\" height=\"661\" srcset=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-4-HHI-1024x661.png 1024w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-4-HHI-300x194.png 300w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-4-HHI-768x496.png 768w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-4-HHI.png 1512w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<h6 style=\"text-align: center;\"><em><span style=\"font-size: 10pt;\">Source:\u00a0 Symphony Health Solutions, Fideres&#8217;s calculations<\/span><\/em><\/h6>\n<h2>Fideres&#8217;s Analysis<\/h2>\n<p style=\"font-weight: 400;\">Fideres has analyzed the entire universe of generic drugs and calculated price changes over the period 2013-2016. The list was then narrowed down to include only generic drugs that experienced an increase in price by more than one manufacturer of more than 250% during this time period.<\/p>\n<p style=\"font-weight: 400;\">Included in the drug list were the various forms and dosages that the generic drugs were available in. These drugs were sorted according to the various price increases. This produced a list of around 180 drugs which experienced a price increase of 250% or more.<\/p>\n<h2>Results<\/h2>\n<p style=\"font-weight: 400;\">The outcome of Fideres&#8217;s analysis is a shortlist of over 90 drugs that experienced significant price hikes combined with similar timing of sales increases between 2013 and 2016.<img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-29076 aligncenter\" src=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases.png\" alt=\"\" width=\"2730\" height=\"1343\" srcset=\"https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases.png 2730w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases-300x148.png 300w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases-1024x504.png 1024w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases-768x378.png 768w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases-1536x756.png 1536w, https:\/\/fideres.com\/wp-content\/uploads\/2017\/01\/Picture-3-of-Drugs-with-Price-Increases-2048x1007.png 2048w\" sizes=\"(max-width: 2730px) 100vw, 2730px\" \/><\/p>\n<h6 style=\"text-align: center;\"><em><span style=\"font-size: 10pt;\">Source:\u00a0 Bloomberg data, Fideres&#8217;s calculations<\/span><\/em><\/h6>\n<ul>\n<li>The overall average increase in price using Fideres&#8217;s methodology during this three year period was over 95%<\/li>\n<li>The shortlisted 90 generics have an average price increase of over 1,350% using Fideres&#8217;s methodology<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A pill of wisdom.<\/p>\n","protected":false},"author":10,"featured_media":28493,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[85],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.8 - 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